In women who have already gone through menopause, Aromasin is used to treat hormone receptor-positive breast cancer in its early and advanced stages.
The drug Aromasin is often administered after other cancer therapies such as chemotherapy, surgery, or radiation for early breast cancer, which is cancer that has not spread outside of the breast. Aromasin is used to treat early breast cancer that has not spread beyond the breast.
It is also used to treat advanced breast cancer that has progressed outside of the breast after being treated with the hormone therapy tamoxifen, as well as other types of cancer.
Read also about effect of exemestane
A variety of FDA-approved applications for Aromasin and Arimidex exist, but they are both used to treat specific forms of early and advanced breast cancer, including triple-negative breast cancer.
Aromasin and Arimidex were used in two clinical trials conducted in 2013 and 2018 to treat early hormone-dependent breast cancer, and their efficacy and safety were directly compared.
Both therapies were found to be equally effective, according to the researchers. After 5 years of therapy with either Aromasin or Arimidex, cancer survival rates varied from 88 percent to 90 percent, according to the findings. The number of participants who were still alive at the conclusion of the research is referred to as the survival rate.
Exemestane 25 Mg Tablet Aromatase Inhibitors: How Should They Be Used?
Before you begin taking exemestane, read the Patient Information Leaflet issued by your pharmacist. You should also read it every time you obtain a refill. If you have any questions, you should speak with your doctor or pharmacy.
By mouth, take this medicine once a day with food (typically after eating a meal) or as instructed by your doctor.
Dosage is determined by your medical condition, reaction to therapy, and any other drugs you may be taking at the time of administration. Make sure to inform your doctor and pharmacist about all of the products you are currently using (including prescription drugs, nonprescription drugs, and herbal products).
To obtain the best effect from this drug, it should be used on a regular basis. Take it at the same time every day to make it easier to remember.
Given that this medicine may be absorbed via the skin and the lungs, women who are pregnant or who may become pregnant should avoid handling the medication or inhaling dust generated by the tablet manufacturing process. (See also the section on Precautions.)
If your situation worsens, notify your doctor as soon as possible (such as you get new breast lumps).
Symptoms and Consequences
Nausea, diarrhea, and dizziness are common side effects, as is hair loss, joint/bone/muscle pain, exhaustion, unusual perspiration, nausea, diarrhea, and problems sleeping If any of these side effects continue or worsen, contact your doctor or pharmacist as soon as possible.
Please keep in mind that this medicine has been recommended by your doctor because he or she has determined that the benefit to you outweighs the risk of adverse effects. The majority of individuals who use this medicine do not have any substantial adverse effects.
If you have any significant side effects, such as bone fractures, mental/mood problems (such as sadness or anxiety), vaginal bleeding, persistent nausea/vomiting, unusual fatigue, dark urine, or yellowing eyes or skin, call your doctor straight once.
This drug (as well as cancer) may cause uncommon but significant issues due to blood clots (such as heart attack or stroke). Take immediate medical attention if you experience any of the following symptoms: shortness of breath, chest/jaw/left arm pain, confusion, coughing up blood, sudden dizziness/fainting, pain, swelling, or warmth in the groin or calf, tingling, weakness, or numbness in the arms or legs, difficulty speaking, swelling of the arms or legs, weakness on one side of the body, vision changes, or sudden/severe headache.
It is very unusual for this medication to cause a life-threatening adverse response. However, get medical attention as soon as possible if you have any of the following symptoms of a major allergic reaction: rash, itching/swelling (particularly of the face, tongue, throat, and neck), extreme dizziness, or difficulty breathing..
Please note that this is not an exhaustive list of probable negative effects. Consult your doctor or pharmacist if you notice any additional side effects that are not mentioned above.
You should tell your doctor or pharmacist if you are allergic to exemestane or if you have any other allergies before starting therapy with this medication. If this product includes inactive compounds that might cause allergic reactions or other issues, it is conceivable that these will occur. Consult with your pharmacist if you need any further information.
If you are using prescription drugs, you should consult with your doctor or pharmacist before starting. Notify them of your medical history, which should include high blood fats (cholesterol), bone problems (such as osteopenia and osteoporosis), stroke and blood clots; cardiovascular illness (such as chest discomfort, heart attack, or heart failure); high blood pressure; as well as kidney and liver issues.
You may experience dizziness or exhaustion when using this drug. If you drink alcohol or marijuana, you may have increased dizziness (cannabis). Do not go behind the wheel, operate machinery, or participate in any activity that needs your full attention unless you are certain that you can do so safely. Keep the alcoholic beverages to a bare minimum. If you are a marijuana user, you should speak with your doctor about your options (cannabis).
Before having surgery, tell your doctor or dentist about all of the medications and supplements you use on a regular basis (including prescription drugs, nonprescription drugs, and herbal products).
When it comes to pregnancy, this medication should be avoided at all costs. It has the potential to cause harm to a developing youngster. Exemestane is primarily administered to women who have gone through menopause and are experiencing symptoms. If you are approaching menopause or have not yet reached menopause and your doctor has suggested that you use reliable forms of birth control, it is critical that you discuss this with him or her before proceeding. When utilizing birth control after stopping this medication, you should continue to use it for at least one month after you stop using the medication. The use of birth control products that include estrogen is not suggested. Consult with your doctor if you need any further information. If you get pregnant or believe that you may be pregnant, you should see your doctor as soon as possible. (See also the section on How to Use for further information.)
It is presently unknown whether or not this medication is excreted in human breast milk. Breast-feeding is not recommended during treatment with this medicine or for the first month after stopping treatment, unless absolutely essential, due to the possible harm to the infant. Make an appointment with your doctor before starting to breastfeed.
It is critical that your doctor monitor your progress on a frequent basis to ensure that the medication is functioning correctly for you. It is possible that blood tests will be required to monitor for side effects. It is critical for women using this medication to undergo frequent gynecologic examinations while taking it.
It is quite rare that a postmenopausal woman will get pregnant again. However, you should be aware that taking this medication while you are pregnant may cause damage to your unborn child. If you are a woman who is capable of bearing children, your doctor may recommend that you have a pregnancy test seven days before you begin taking this medication to ensure that you are not pregnant. When using the medication and for one month following the last dosage, use an effective method of birth control. If you suspect that you may have gotten pregnant while using this medication, contact your doctor immediately.
When used for an extended period of time, this medication may cause a reduction in bone mineral density. A low bone mineral density may result in brittle bones or osteoporosis, which are both serious conditions. If you have any concerns regarding this, you should consult with your physician.
For further information, talk to your pharmacist or doctor about your options.
What is the reason for prescribing this medication?
Exemestane is a medicine that is used to treat early breast cancer in women who have gone through menopause (also known as ‘change of life’; the cessation of monthly menstrual cycles) and who have previously been treated for 2 to 3 years with a prescription called tamoxifen (Nolvadex). It is also used to treat breast cancer in women who have had menopause and whose breast cancer has deteriorated while they were on tamoxifen, according to the FDA. Exemestane is a medicine that belongs to a family of drugs known as aromatase inhibitors. It works by reducing the amount of estrogen that the body produces naturally. Some breast cancers that need estrogen to develop may be slowed or prevented from growing as a result of this treatment.
What is the proper way to administer this medication?
Exemestane is available in the form of a tablet that must be swallowed. It is normally used once a day, after a meal, and is not addictive. Take exemestane at the same time every day in the same place. Continue to carefully read and follow the recommendations on your prescription label, and ask your doctor or pharmacist to clarify any parts of the instructions that you do not understand. Exemestane should be taken precisely as advised. You should not take more or less of it, or take it more often, than your doctor has recommended.
For many years or maybe longer, you may need to take exemestane. Even if you are feeling well, you should continue to take exemestane. Do not discontinue taking exemestane without first seeing your doctor.
See also Cancer Treatment With Aromasin (Exemestane)
Which factors should I consider while deciding whether or not to take Aromasin?
Aromasin should not be used if you are pregnant, nursing, or are still experiencing menstrual periods.
Aromasin should also not be used by anybody who is allergic to the medicine or any of its constituents, according to the manufacturer.
In addition to Aromasin, what other medications have interactions with this medication?
When using Aromasin, stay away from estrogen and estrogen-containing products such as hormone replacement therapy and birth control pills. Aromasin may interact with a number of over-the-counter herbal remedies that contain plant estrogens, including several herbal teas.
What Other Medications Have Similar Effects?
Anastrozole (Arimidex) and Femara (Femara) are two more drugs that fall under the category of aromatase inhibitors (letrozole). The second mechanism by which these drugs function is by preventing the conversion of other hormones, known as androgens, into estrogen. These drugs should not be used in conjunction with Aromasin.
What is the purpose of Aromasin?
Aromasin is a medication that is used in the treatment of breast cancer. It may be used as a post-operative medication following surgery, chemotherapy, and/or radiation. It may also be used to treat breast cancer that has progressed to the stage of metastatic disease, meaning that it has spread to other parts of the body, after treatment with tamoxifen.
What is the mechanism of action of Aromasin?
After menopause, the body continues to manufacture estrogen by converting another hormone type, known as androgens, into the estrogen we know and love. Aromasin prevents this process from taking place, resulting in a reduction in the quantity of estrogen in the body. When a person is diagnosed with hormone receptor-positive breast cancer, the presence of estrogen in the body is required for the tumour to develop. When estrogen production is inhibited, cancer cells are unable to use estrogen as a growth factor.
Are Aromasin’s negative effects anything to be concerned about?
Aromasin may cause a variety of side effects, including the following:
Flashes of heat
Fatigue and joint discomfort
Sleeping problems are a common occurrence.
What can I do to maintain my health while taking Aromasin?
Maintaining compliance with your Aromasin medication for the specified period of time is a key aspect of breast cancer treatment success. If you have any negative effects with Aromasin that cause you to wish to discontinue treatment, communicate with your healthcare provider immediately. They may be able to assist you in coping with these side effects or may have other recommendations to make you feel more comfortable.
See also The Definitive Guide to Anti-Estrogen Drugs and How They Function